本季将去到拉斯维加斯，继续为人们“换新”生活，从一个找不到自信的前演出女孩到一个专心工作、需要一些变化的图书管理员。
John Mulaney returns to his Chicago high school with David Letterman as they candidly discuss addiction, fatherhood and the state of stand-up comedy.
