故事延续着第一季六位主人公的生活。英国式的对白，英国式的幽默。该剧荣获2003年英国喜剧大奖最佳电视喜剧。
A lone crimefighter battles the forces of evil with the help of an indestructible and artificially intelligent supercar.
Chatfah, the youngest sister of the Bupphachinda family, has just received the largest share of her father's inheritance and is about to be married. However, Chatfah falls from the highest floor of a vacation home to her three older sisters' shocked eyes. When her body disappears, her three sisters—Baibua, Chomphu, and Picha—become suspects in her disappearance. The eldest sister Baibua is composed, wise, and has always sacrificed for her family. The second, Chomphu, is a confident model whose boyfriend Chatfah stole and was engaged to. The third, Putpichaya, is a jewellery designer and the closest to Chatfah. The three search for Chatfah while further tragedy befalls them following their youngest sister's disappearance. When no one else can be trusted, the three sisters must try to trust one another. They move back to their childhood mansion to find out who was behind Chatfah's disappearance, which could very well be one of them.
《神秘博士》第13季宣布开拍。运作人Chris Chibnall透露新季将缩短为8集，因为该剧拍摄的复杂性，在新冠疫情下拍每一集所需的时间延长了，“不过《神秘博士》的雄心、幽默、乐趣和惊吓是不会少的。如今对全世界来说充满考验，但博士从不逃避挑战”。
